(1965).Ĭases of stub thumbs have also been found in Eastern Nepal for Jirel ethnic individuals from their participation in various epidemiologic studies. However, as the survey's Arab test persons were mainly recruited from a handful of large and closely related clans living in a particular village, said percentage should be "considered with some reservation," according to Goodman et al. Hereditary trait Ī 1965 scientific study in Israel found that 3.05% of Israeli Arabs had one or two stub thumbs, compared with 1.57% among Ashkenazi as well as non-Ashkenazi Jews.
Various other studies supported an autosomal dominant pattern with reduced penetrance. The condition is associated with the HOXD13 gene, which is central in digital formation and growth. Genetics Ī genetic trait, brachydactyly type D exhibits autosomal dominance and is commonly developed or inherited independently of other hereditary traits. The condition may either be unilateral (affecting one thumb) or bilateral (affecting both). Stecher (1957) claimed that it is approximately two-thirds. Breithenbecher (1923) found that distal phalanges of stub thumbs were one-half the length of full-length thumbs, while R.M. It is the most common type of brachydactyly, or shortness of digits, affecting approximately 2–3% of the population, and is associated with the HOXD13 gene, located on chromosome 2q31.1 Physiology īrachydactyly type D is a skeletal condition which exhibits a 'partial fusion or premature closing of the epiphysis with the distal phalanx of the thumb', according to Goodman et alia (1965). The distal phalanx of affected thumbs is approximately two-thirds the length of full-length thumbs. X-ray of a normal thumb (left) and a thumb with brachydactyly type D (right) showing distal phalange brachyphalangy of said thumb.īrachydactyly type D, also known as short thumb or stub thumb and inaccurately referred to as clubbed thumb, is a condition clinically recognised by a thumb being relatively short and round with an accompanying wider nail bed. Unilateral brachydactyly type D in a 15-year-old female Clubbed thumb, club thumb, short thumb, potter's thumb, royal thumb, murderer's thumb, toe thumb, hammer thumb, stubbed thumb, stub thumb
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